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Re: Remeron and agitation » krista

Posted by JohnX2 on November 1, 2001, at 0:40:11

In reply to Remeron and agitation, posted by krista on October 31, 2001, at 20:51:19


Is that a typo on the 37 milligrams?
Usually Remeron is dispresed in increments
of 5 mg. Typically start at ~10-20 and go
upto 45 mg.

Here is some useful information about Remeron,
but I don't know if it will answer the specifics
of your question

- Remeron is an antihistamine (like benadryl)
At the lower doses, this is generally thought
to be responsible for sedation and weight gain.
You may grow tolerant to the anti-histamine
side effect over time. PS. benadryl is the
most common OTC sleep aid.

- At the higher doses (say 30-45 mg) remeron
starts to act more at noradrenergic brain receptors.
It will have a general trend of become more
stimulating (and possiblity causing anxiety), but
generally with more anti-depressant kick and some
offset of the anti-histamine drowsiness.

The time it takes for the side effects to subside
is a very individual matter. For some people it
will be the same day for others in could be 2 weeks.

I'll say that at a given dose, I would hope that most
of the side effects would have subsided after about
2-3 weeks. My experience on anti-depressants is that
if I can't get over the side effects on a fixed dose
after 3 weeks, then usually the side effects don't
drop enough to make the med bearable. But that is
just me and everyone is different.

-john

> Hello,
>
> I just started remeron 2 weeks ago. I went up to 37 mg and
> felt very sedated and weird. I'm back to 30mg. now.
> It seems the higher I go the more out of it I feel. But at 30 mg. I'm still feeling depressed. (Maybe I haven't given it enough time?)
> The side effects I felt at 37 mg. were extreme pressure in my head, numbness, even my teeth felt numb. And right after the intitial
> dose before bed, I would get easily startled by noises and feel restless and agitated as well as sedated at the same time. I was on 37 mg for a week and the side effects were not getting much better.
> Has anyone had increase in side effects whith increase of Remeron. Maybe I just need to go up real slow.
> I did increase the Remeron rather quickly in the beggining.
> Does anyone else notice agitation with higher doses of Remeron. Also does it take longer than a week for the side effects to subside?


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poster:JohnX2 thread:82805
URL: http://www.dr-bob.org/babble/20011025/msgs/82824.html