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Re: Dothiepin Query

Posted by SLS on October 6, 2001, at 21:19:37

In reply to Dothiepin Query, posted by SalArmy4me on October 6, 2001, at 18:17:01

> Does Dothiepin work on just norepinephrine, like desipramine or maprotiline? Or is it a dual reuptake inhibitor like imipramine or venlafaxine? {I've been on it for 11 days, along with mianserin and amisulpride}.

That's a very interesting combination. It sounds pretty good. Good luck with it. I think it is pretty similar to the other tertiary tricyclics in that it does offer some inhibition of the reuptake of 5-HT along with NE.

Something I came across a few days ago sparked my interest in dothiepin, but I can't remember exactly what. I wish I could remember where I saw it.

Ok. Found it.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10379421&dopt=Abstract

I was interested in it because it was reported to be an antagonist at the 5-HT2 receptor.


- Scott

 

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