Posted by mgrueni on September 7, 2001, at 13:24:21
In reply to Re: Cam, could you please explain me something?, posted by Cam W. on September 7, 2001, at 9:53:39
Hello Cam,
< I like to use the "automobile as human body" analogy. It he brain were the engine, then when we get down to the neurotransmitter level, we can equate (say) serotonin to spark plugs of the electrical system. Now, an isolated spark plug does not do much; it does not tell us how the car runs. We have to step back from the spark plug to see how it works in relation to the rest of parts it attaches to (and also what those other parts attach to). >
Yes, I`ve heard of this analogy and it seems quite logical to me. Thanks for reminding me of it (I forgot *so* much of what I learnt at pharmacy school) :o)
< Serotonin: Involved in: sleep initiation, impulsivity, mood modulation, pain modulation, modulation of aggression, control of anxiety, maintenance of alertness. Norepinephrine: Involved in: sleep maintenance, mood modulation, energy, interest, vigilance, self-perception Serotonin + Norepinephrine + Dopamine: Involved in: mood, emotion, and cognitive function. >
Ah, that were the basics I was looking for - you wouldn`t believe how difficult it is to find some useful answers to medical related questions in german language on the net. All sites which possibly would give such answers are key-word protected (doctors only) :o(
A far more in depth explanation can be found at the following website:
http://www.acnp.org/g4/4thgen.php
It will take me some time to read it, but this also seems to be very useful.
< As for the pharmacology of Kava Kava, I have no idea. I have never seen serotonin syndrome result from the use of an SSRI and Kava Kava. I have seen some fairly nasty, flaking rashes result from the use of high doses of Kava Kava, over a long period of time, though. >
Yes? Rashes? That`s news to me.
But, I think I will not recommend Kava Kava in combination with Effexor, as long as there are no new reasearches which say that it definitely isn`t dangerous - better too careful than too experimental. It seems, valerian is working quite good on my friend, so I hope that will solve the problem.
< I hope that this (and the link) are of some use to you. - Cam >Yes, thank you :o)
Micha
PS: please excuse my rather formal and brief reply (unusual for me....) but I have a very bad headache at the moment, and can hardly concentrate on anything.
poster:mgrueni
thread:78136
URL: http://www.dr-bob.org/babble/20010907/msgs/78176.html