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Re: Wellbutrin SR vs IR » sl

Posted by shelliR on September 1, 2001, at 19:01:10

In reply to Re: Wellbutrin SR vs IR ------ SL and terra miller, posted by sl on September 1, 2001, at 9:27:25

Hi sl,

A couple more questions, please.

What was your dose when you were on the SR? Were you up to 400mg, or if you go back to it, it would be an increase?

Also, how long, if you remember, did it take for the wellbutrin to kick in a little, and then full force?

And last, are you taking anything else for depression in combination with wellbutrin?

Today was the first day I didn't feel totally hyper since I've been on 200 SR, but I'm not sure if I have any antidepressant effects yet. Not sure, because both yesterday and today I didn't wake up in a total overwhelming depression for the first time in quite a while. I did have breakthrough depression (I am combining with an opiate which has been carrying me until an AD works), so maybe after a week or so on 300 mg I will have more of an idea. I hope it works; I've tried about everything else; I like the energizing effect on me, as well as my lack of appetite since I'm trying hard-- eating--treadmill-weights--to lose 20 pounds more. (Lost 10 since early April).

Shelli


> I was on IR long ago, before SR came out, for several years. And my GP (who was maintaining my meds at the time) switched me to SR because most people respond better. But within 6 months of switching, I could see the difference in mood. And after a year or two, I started developing anxiety. (I thought it was just me, but I talked to an expert psychiatric nurse and she said she's seen some [anecdotal] evidence that long-term use of SR can cause anxiety.)
> I decided to go back to the IR in hopes of banishing the anxiety and returning my mood to its previous state (good!).
>
> I will state that even Wellbutrin SR was better for me than Effexor, Nortriptyline, Prozac, all of which I tried over this summer before deciding to go back on the IR Wellbutrin.
>
> Dosage has been weird tho.
> I found out that Wellbutrin IR dosage is better absorbed than SR, so if one is taking IR and then switches to SR, the dosage should be raised slightly (mine wasn't!).
> And the people prescribing it now say I should take 75mg 4x day. But if they think I'm going to remember that, then THEY are the crazy ones. Besides, I'd have to get that last dose MIGHTY close to bedtime, so I'd still have insomnia. I'm going to take it twice/day unless side-effects get too extreme. I might try 100mg 3x day, but that's only if I can't tolerate 150 2x day, which is what I was on before. The last thing to try is taking 200mg SR 2x day.
>
> So that's the REST of the story. ;)
>
> sl


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