Posted by JahL on August 30, 2001, at 19:57:40
In reply to Re: Foreign Medications » JahL, posted by SLS on August 29, 2001, at 20:49:25
>
> > Sulpiride (Dogmatil) for social phobia/dysthymia (similar to Amisulpride tho they have dramatically different effect upon me).
> >
> > J.
>
>
> Hey J.
>
> How 'ya doin'?
>
> I am quite interested to know how you would describe the differences in your reactions to sulpiride versus amisulpride.Hi Scott.
It's hard to tell what Amisulpride did, if anything. When I tried it, at 25mg & 50mg (possibly higher) I wasn't confident enough to completely stop the Sulpiride & as my social phobia became worse I can only deduce that the Amisulp. wasn't helping.
Sulpiride provides consistent, if not complete relief from social phobia symptoms & not just in the way that a benzo or beta-blocker might calm someone (not me). Paranoid thoughts; the idea that you are particularly conspicuous, and ruminations are lessened. Beyond 150mg no further benefits are accrued & sedation sets in. It's been the most helpful drug for me so far.
The drug that led me to Sulp. is interesting. Promazine, a sedative with mild antipsychotic properties would bring about say, a 20% remission from baseline within 2 hours of taking a pill. And I can replicate this time & time again. Further proof that my complaint is a biological one. Had to stop due to EPS, slurring of speech & slight paranoia. Enter Sulpiride.
> On a related topic, I was dismayed this morning to learn that NeuroSearch has suspended their investigations of brasofensine.Me too. Stahl mentions it as a promising drug in his Essential Psychophamacology... book.
> All of these drugs seemed viable to me, and I feel demoralized that there should be fewer alternatives to hope for in the future.
You're not alone on that one. Not sure if I have any options left aside from clinical trials (just been referred to the world's first Depersonalisation Research Unit) :-(
J.
poster:JahL
thread:76877
URL: http://www.dr-bob.org/babble/20010828/msgs/77011.html