Posted by Rick on August 26, 2001, at 0:25:33
In reply to Re: Xanax and panic, Elisabeth, more. » Thrud, posted by Rick on August 24, 2001, at 1:32:59
>Please let me thank you for your excellent and encouraging posting. Unfortunately for you, since you were so helpful I am afraid I must "pick your brain" a bit more! (I apologize beforehand.)
Happy to oblige, but I think the “pickin’s” may be getting slim.
> > Forgive me if you’ve already addressed this earlier in thread, but when you were on Remeron did you try augmentation strategies to restore sexual function? I recently read a study of augmentation with Wellbutrin (as I recall) that showed no significant restoration of sexual function vs. placebo. They both "worked" in something like 30% of the subjects.
>I have tried these as augmentaion therapies and they both further *reduced* my sexual function!
>So did Gingko and L-Tyrosine! Viagra is okay for erection but does nothing for my desire or sensation (takes away the 'sponteneity' of sex as well).
>The one you mention that I have not tried but has me interested is deprenyl. I am sceptical though because it is supposed to work by increasing dopamine...like Wellbutrin: and that failed.
Despite the dopamine-connection to smoking and Wellbutrin’s double-role as Zyban, WB’s mechanism of action is pretty fuzzy. It’s now thought that noradrenergic effects, unknown effects, or both, account for more of Wellbutrin’s efficacy than dopaminergic actions. Insofar as dopamine reuptake inhibition, it’s been shown that this doesn’t occur much, if at all, at the dosages prescribed for depression (and of course doses used for augmentation are even lower).
Nonetheless, I had assumed, perhaps incorrectly, that dopamine underlied the anxiety Wellbutrin added back when used it to augment a Klonopin/Celexa combo. Maybe that bothersome effect would’ve subsided had I given it more time. As usual, based on what others have posted here, Wellbutrin-worsened anxiety goes away for some people but not others.
The reason for augmenting Klonopin+Celexa with WB was to fight fatigue/apathy and improve sexual function. It helped mildly on the zone-out problems, but didn’t make a difference sexually. But I didn’t give it a fair trial, because it was adding back anxiety and I didn’t really care for Celexa much anyway. (That’s when I added Serzone+Provigil to the K that's still going strong after 15 months.)
The short WB trial, plus the fact that I took it with a sedating and sexual-dysfunction-inducing AD, means there’s no way for me do make a direct firsthand comparison with selegiline. (Remember, I was taking selegiline with 2-3 mg Klonopin, which has never produced sexual dysfunction for me.) But the selegiline was such a potent sexual activator that my guess is you’d have a much better shot at reducing or eliminating benzo-induced sexual dysunction augmenting with very-low-dose selegiline, than you had trying to reverse AD-induced sexual side effects with WB.> > You may have already tried these suggestions, but you should go to the full-search page on this site, and you’ll come up with tons of personal experiences. Or just browse. And post again if you don’t get more responses to this. Also, if you haven’t already done so, visit and/or post and/or search through Usenet, especially alt.anxiety.panic. (You can do this all free through http://groups.google.com )
>I will do this, espescially for the million dollar question: If I wait long enough, *will* my libido return when on benzos??????
>Could I ask you a big favor? If you are firmly "enmeshed" in any of these groups, could you ask the million dollar question on my behalf and let me know the result? I have found that being a newbie often leads to being ignored, probably from asking questions that have been asked a zillion times before.
Actually I’m anything but “enmeshed” in Usenet! I’ve only posted to the newsgroups a handful of times. I’ve ususally ended up there when doing searches for a specific topic. For that matter, I wouldn’t call myself a “regular” on Psycho-Babble, either. I tend to post a lot for a week or two at a time, and then don’t visit again for up to a couple months, unless I receive one of those automatic e-mail notifications that a thread of interest has had some new activity. If you’re concerned about anonymity, set up a free e-mail address with, say, Yahoo, then register free with Google Groups (link above), use that to post o Usenet via the web, and then cancel the email account.
Rick
poster:Rick
thread:76063
URL: http://www.dr-bob.org/babble/20010822/msgs/76423.html