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Re: Does wellbutrin sr work for anxiety? » Janelle

Posted by paxvox on August 16, 2001, at 17:31:52

In reply to Re: Does wellbutrin sr work for anxiety? » AVR, posted by Janelle on August 16, 2001, at 13:11:45

> I THINK that part of the reason why Wellbutrin often increases anxiety is because it acts on Dopamine receptors, and increasing Dopamine has been found to be activating.

Well, yes and no. Wellbutrin is not a dopamine agonist,nor does it bind to dopamine receptors in the CNS. It is postulated that it DOES allow more free-floating dopamine to remain in the sytem. It is the GABA receptors, to which the benzodiazepines have an affinity, that affect the "calm" state of mind. WB definitely does not make one calm.


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