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Re: Can someone interpret this? » grapebubblegum

Posted by SalArmy4me on August 16, 2001, at 12:57:48

In reply to Can someone interpret this?, posted by grapebubblegum on August 16, 2001, at 8:34:31

Site of Action - Consequences of Blockade

Histamine-1 receptor - Sedation, antipruritic effect

Muscarinic acetylcholine receptor - Dry mouth, constipation, sinus tachycardia, memory impairment

Norepinephrine (NE) uptake pump - Antidepressant efficacy, increased blood pressure, tremors, diaphoresis

Serotonin (5HT2) uptake pump - Antidepressant efficacy, nausea, loose stools, insomnia, anorgasmia

5-HT2A receptor - Antidepressant efficacy, increased REM sleep, anti-anxiety efficacy, anti-EPS

Alpha-1 NE receptor - Orthostatic hypotension, sedation

5-HT2C receptor - Anti-anxiety efficacy, increased appetite, decreased motor restlessness

5-HT3C receptor - Antinauseant

Alpha-2 NE receptor - Antidepressant efficacy, arousal, increased libido

Sodium fast channels - Delayed repolarization leading to arrhythmias, seizures, delirium


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URL: http://www.dr-bob.org/babble/20010814/msgs/75293.html