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Don't split or divide SR or XR formulated tablets

Posted by Cressida on August 14, 2001, at 20:59:34

In reply to Wellbutrin SR Side Effects and Pill Splitting, posted by Remi on August 14, 2001, at 5:35:00

>Can 100mg or 150mg pills be split to dial in a >comfortable dosage w/o stomach harm? I >prefer .the SR due to the lower seizure >incidence. I take a 100mg pill in am, then half >of one in evening in hopes of spreading out the >dosage and easing this side effect. I will >probably drop to 100mg until I pass through this >stage.

Quoted from "The PDR Pocket Guide to Prescription Drugs":
You should take Wellbutrin SR, the
sustained-release form, in 2 doses,
at least 8 hours apart. Swallow Well-
butrin SR tablets whole; do not chew,
divide, or crush them.

Therfore, I wouldn't recommend "splitting" the tablets; dividing one probably destroys or disrupts the "sustained-release" mechanism.


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poster:Cressida thread:75031
URL: http://www.dr-bob.org/babble/20010814/msgs/75094.html