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Re: Buspirone (BUSPAR) cause fatigue? » Cindylou

Posted by Mitch on August 12, 2001, at 14:51:17

In reply to Re: Buspirone (BUSPAR) cause fatigue? » Mitch, posted by Cindylou on August 12, 2001, at 12:23:11

> Thanks for the info, Mitch. Yes, I am VERY med sensitive -- had to start at 2.5 mg. Prozac because of my reactions.

I could only tolerate 5mg/day max. and only during my seasonal depressions otherwise 2.5mg/day was what I took most of the year.

>
> Do you think Buspar would help me -- currently, on my Wellbutrin + Prozac combo, I am either very agitated or very exhausted -- OR agitated and exhausted at the same time (if you can imagine that.) I wonder if Buspar + Prozac would make a difference? (eliminating the Wellbutrin).
>

The agitation I would suspect is the Wellbutrin. It sounds like these periods of agitation happen during the course of the day? Wellbutrin has a very short half-life compared to Prozac's very long half-life. The blood levels could be varying a lot causing that. Was the WB added because you were very tired?


> I am going to start a new thread about adding Adrafinil to that mix as well. Do you know much about Adrafinil?

I wouldn't mess with adding yet another med if the ones you currently are taking may be causing the problem. You will have to try everything one step at a time and try to be patient (I know it is hard!).

My suggestion (first thing) is see if you can take a lower dose of Wellbutrin more frequently during the day to see if that levels it out. I know the smallest SR formulation is 100mg, but maybe you are on 150mg SR twice a day. So try 100mg SR 3x daily and see what happens. If you are taking a lower dose of WB, then you would have end up chopping pills and there is a lot of controversy about doing that-but if you are taking Prozac 2.5mg/day then you are either on the "liquid" or making your own liquid! (which is what I did).

Mitch


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