Posted by Elizabeth on August 9, 2001, at 16:47:27
In reply to Re: sleep stuff » Elizabeth, posted by paxvox on August 9, 2001, at 11:15:30
> I didn't say that they didn't "cross tolerate", however, they are diffent enough in degrees such as half-life, etc where one can be used to maintain the effects of another where the subject has becomer tolerant to that specific chemical formula.
I wouldn't expect that to happen. A person who's tolerant to Valium will also be tolerant to Serax, for example. In this case, taking the equivalent dose of Serax would prevent withdrawal symptoms, and taking a higher dose than the equivalent one would produce a positive effect. The minor variations in the chemical structures of various benzodiazepines don't make a difference here; their pharmacodynamics are the same, and that's what matters.
Partial cross-tolerance does occur with other classes of drugs that have related, but not identical, mechanisms (such as alcohol or barbiturates).
-elizabeth
poster:Elizabeth
thread:72451
URL: http://www.dr-bob.org/babble/20010809/msgs/74359.html