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Re: MAOIs and sleep problems » Grouch

Posted by Elizabeth on August 5, 2001, at 8:12:07

In reply to MAOIs and sleep problems, posted by Grouch on August 4, 2001, at 21:26:44

> MAOIs (Parnate & Marplan) are the only antidepressants that have been helpful for me. Unfortunately, I'm not able to tolerate them due to numerous side effects, especially sleep problems (insomnia, disrupted sleep cycle).

That was a problem for me with MAOIs too. Their widespread effects on aminergic systems seem to blow the whole circadian cycle to bits. I have a book somewhere that discusses their effects on sleep in depth, but I'd need to dig around to find it (I moved recently).

Adding Ambien to the MAOI was somewhat helpful for me, and I didn't grow tolerant to it.

One thing that's sometimes suggested is melatonin. I'm not too sanguine about adding that to MAOIs, though: when I tried a small amount, it kept me up all night (even with Ambien), I was sweating excessively, and my pupils were very dilated.

-elizabeth


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poster:Elizabeth thread:73594
URL: http://www.dr-bob.org/babble/20010804/msgs/73645.html