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GHB and narcolepsy » Else

Posted by Elizabeth on August 4, 2001, at 23:31:15

In reply to Re: JohnLplease help me with this, you might know too! » gldngodess, posted by Else on August 3, 2001, at 18:36:41

> I thought narcolepsy involved too much sleep. What does GHB have to do with it?

Narcolepsy is not hypersomnia. People with narcolepsy have attacks of REM sleep during the daytime. The attacks are often triggered by strong emotions.

REM-suppressing drugs (for example, MAOIs, amphetamine, and some tricyclics) are the main treatments for narcolepsy at present. GHB has stabilising effects on REM sleep and prevents the intrusion of REM sleep upon waking states.

GHB may also be useful for other sleep disorders. I would be very curious to see what effect it would have on my peculiar problem (currently under control with desipramine + clonazepam).

Like some other so-called "drugs of abuse," GHB is an endogenous drug: it occurs naturally in the human body (it's closely related to GABA). This would seem to make its Schedule I status rather problematic.

-elizabeth


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