Posted by Lorraine on August 1, 2001, at 10:46:03
In reply to Re: TREATMENT RESISTANT DEPRESSION - INFO NEEDED, posted by JohnL on July 31, 2001, at 4:33:20
> Disclaimer, mileage varies. However, in my experience, treatment resistant depression usually means the doc and the patient are barking up the wrong tree. In other words, they are trying drugs in the wrong category.
>
> It's a hit-and-miss game, since we all have unique chemistries, unique problems in those chemistries, unique genes, unique personality and circumstances. Based on what I have seen in others over the years, based on exhaustive research, and based on this board, the highest potential for success in TRD involvs combinations of any of these:
> Prozac
> Zyprexa
> Adrafinil
> Amisulpride
> Risperdal
> Forget everything else until these have been exhausted. My TDR has been successfully treated with 20mg Prozac + 5mg Zyprexa + 300mg Adrafinil. It is worth noting that while these drugs are working miracles for me, they are doing so at the minimum doses. It's just my opinion, but the farther away a drug is from treating the true underlying problem, the higher the dose is required. The closer it is to the real problem, the lower the dose.
> John
John: Just want to say it's nice to see a success story and to see you still giving on the board. When I read your posts it makes me happy. I had a partial response to prozac years ago--I'm reluctant to go back on it because it takes so long to go off it. Also my pdoc is not yet at the point where he'd be willing to try Adrafinil. (He may get there--we still have some major drug classes to work thru--I'm on Parnate now, day 2). Still, I keep your little recipe for success in the back of my mind and appreciate your posts. :-)
poster:Lorraine
thread:72327
URL: http://www.dr-bob.org/babble/20010731/msgs/72894.html