Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Experience with trileptal? » Emme

Posted by SalArmy4me on July 29, 2001, at 15:03:25

In reply to Re: Experience with trileptal?, posted by Emme on July 29, 2001, at 11:17:52

It once was overwhelmingly helpful until it pooped-out (Tegretol XR).

"Institution
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA.

Title
Valproate and carbamazepine increase prefrontal dopamine release by 5-HT1A receptor activation.

Source
European Journal of Pharmacology. 380(1):R1-3, 1999 Sep 3.

Abstract
The anticonvulsant mood stabilizers valproic acid (250, 500 but not 50 mg/kg) and carbamazepine (6, 12.5 but not 3 mg/kg) were found to increase extracellular dopamine levels in rat medial prefrontal cortex, but not nucleus accumbens. Increased prefrontal dopamine was completely abolished by the selective 5-HT1A receptor antagonist N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexa necarboxamide (WAY100635, 0.05 mg/kg). Anticonvulsants and clozapine may share a common mood stabilizing mechanism since clozapine is reported to have mood stabilizing effects and increase prefrontal dopamine by 5-HT1A receptor activation."


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:SalArmy4me thread:71844
URL: http://www.dr-bob.org/babble/20010725/msgs/72388.html