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Re: clonazepam+depression

Posted by PaulB on July 28, 2001, at 6:21:12

In reply to Re: clonazepam+depression, posted by Benzobuster on July 27, 2001, at 22:12:18

> > > Dear Paul,
> > > My pdoc, the anxiety specialist, feels that in people with primary anxiety klonopin helps the anxiety which in turn reduces depressive symptoms. It should be fairly easy for you to think which symptom was first. Again in people with primary anxiety, SSRI's tend to worsen symptoms of anxiety- which in turn worsen depression. (Personally, SSRI's just make me manic and klonopin is the magic bullet) Hope you're doing better- judy
> >
> > Thanks for the replys. It just recently occured to me that the benzodiazepines may not actually worsen my depression. I think it was that I expected the 'pams' to worsen mt depression and I didnt expect it with the SSRI's I tried. The former are depressants after all. The idea that anxiety can precipitate and cause depression and therefore treating the anxiety alone is a interesting topic but Im not sure where I stand on it.
> >
> > The writer of an article which drew on the topic says:
> >
> > 'My own view is that the notion that benzodiazepines "cause" or "precipitate" depression may be an interpretive error. That is, people with anxiety disorders like social phobia and generalised anxiety disorder are at a higher than average risk of depressive illness across their life span. If someone receives a benzodiazepine, typically they have more severe symptoms, which increases risk. Since benzodiazepines have no maintenance preventative effect for subsequent depressive episodes, and since they are typically taken long-term, the association between benzodiazepines and depression may actually be population at risk effect(i.e. it is the group of people, not the drug, that increases relative risk)
> >
> > Elizabeth, you mentioned Xanax which is a good option I hear. Recalling that particular pdoc I mentioned he added, specifically, that people who are unable to tolerate Clonazepam do much better when switched to Lorazepam.
>
> > PaulB
>
> Paul, Excuse me but the information you just gave out will have the opposite effect as what you think. One does not switch from a medium half life benzo to a short half life benzo and expect it to reduce anxiety. This will cause more problems.
>
> Then you wrote:
> "and since they are typically taken long-term,"
>
> You give the impression that the drug companies endorse long term usage. This is not true. Benzos should not be used for more than 2 to 4 weeks for anxiety or insomnia. Depression ? Just where di anyone here get the idea that a tranquilizer is an anti-depressant. Tranquilizers are depressants and do not lift a persons mood. It may seem that they do because they actually take the edge off and dull the CNS.
>
> There is a web page that was just rated 5/5 by Clinnix. This web page is the best in the world on the subject of benzos.
>
> Dr James Cave reviews medical websites (REF: Clinnix)
>
> The site of the benzodiazepine addiction, withdrawal and recovery group.
>
> Reviewing the site, Dr Cave said: "Possibly the most comprehensive site on benzodiazepines and addiction, this is not a sight for the sensitive doctor! And that is my only criticism of this otherwise great site. Ray Nimmo, the creator, has somehow made it almost addictive with wonderful little back streets, humour and punchy personal stories. I would recommend all GPs and pharmacists visit this site."
>
> Star Rating 5/5
>
> Website address: http://www.benzo.org.uk
>
>
> Source:
> http://www.clinnixpro.net/news/archive/010521
>
> *****PLEASE NOTE*****
> The Heather Ashton Manual on How to Withdraw From Benzodiazepines
> http://members.dencity.com/ashtonpapers/manual.htm
>
>
> News and Articles on Benzodiazepine Issues
> http://www.geocities.com/benzodebate
> Link to All Known Benzo Related Web Sites
> http://www.geocities.com/benzowebsites
> Benzobusters Site of Withdrawal Symptom Lists & The Accidental Addict
> http://members.dencity.com/BenzoBusters
> ""The worst of the withdrawals should be over in about three days. If you're no better in a week, see your GP and he'll give you something. In the meantime get some sleep - you look terrible." (Some young UK Casualty doctor)

PaulB says
Not to disagree with you. Everyone has their own views and I believe that you are right in that the benzodiazepines are certainly not anti-depressants. But I would like to clear up a couple of things where I think you may have misunderstood me.

You wrote that one does not switch from a medium half-life benzo(Clonazepam)to a short half-life benzo(Lorazepam)and expect it to reduce anxiety but in fact this causes more problems. In reference to the pdoc I was taliking about I wanted to highlight that those who couldnt tolerate Clonazepam may do better on Lorazepam because it 'may' be less likely to cause/worsen depression. Lorazepam and other 'shorter-acting benzo's' may well be inferior in terms of their potential for addiction which is where we got our wires crossed.

Secondly, I dont personally think benzodiazepines are anti-depressants. However, in some cases if a person with an anxiety disorder takes a benzodiazepine their depression may lessen because their anxiety disorder made them more susceptible to depression. Although I said I didnt know where I stand on this issue.

Thirdly, you said I wrote
"and since benzodiazepines are typically taken long-term". I didnt write this. I quoted this, unfortunately from a cut-out so I cannot provide the source. So it wasnt me who would be implying that the drug companies endorse benzodiazepines for long-term usage. Your right, the drug companies do not approve of longer periods of usage than you mentioned.


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poster:PaulB thread:71316
URL: http://www.dr-bob.org/babble/20010725/msgs/72212.html