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Re: Dr's RX: Paxil, Klonopin, Ritalin, Ativan, Inderal

Posted by SalArmy4me on July 19, 2001, at 1:00:44

In reply to Dr's RX: Paxil, Klonopin, Ritalin, Ativan, Inderal, posted by Pal on July 18, 2001, at 9:18:58

I say give the Paxil 3 more weeks and if it doesn't work change to a new med:

"A more recent placebo-controlled study by Quitkin et al (1996) reported on 693 patients treated prospectively with a variety of antidepressant regimens. A response criterion was a sustained score on the CGI of much improved or very much improved. All patients were rated weekly. They concluded that those patients with some improvement in depressive signs/symptoms by week 4 should have their antidepressant regimen continued until week 6. This was based on the observation that 39% (versus 8% of placebo) of patients at week 4 that had minimal improvement were responders at week 6. However, if at week 4 the patient has had no improvement, then the treatment should be changed. This was based on the observation that for drug and placebo only 13% and 6%, respectively went on to respond at week 6..."

http://www.vh.org/Providers/Conferences/CPS/11.html


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