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Re: Nortriptyline, Prozac, Wellbutrin....SR? » sl

Posted by SalArmy4me on July 10, 2001, at 13:30:13

In reply to Nortriptyline, Prozac, Wellbutrin....SR?, posted by sl on July 10, 2001, at 11:19:07

I ran the combo through a drug checker, but keep in mind that the drug checker at www.drkoop.com is very reactionary--it comes up with stuff that may not be clinically relevant:

1. Severe Interaction between Pamelor (generic: nortriptyline) and Prozac (generic: fluoxetine)

Marked increases in plasma tricyclic antidepressant levels have been reported after administration of fluoxetine. Seizures and delirium have been reported. The mechanism is likely related to fluoxetine-induced inhibition of the cytochrome P450 system. Caution and close observation for evidence of tricyclic toxicity are recommended if these drugs must be used together.


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URL: http://www.dr-bob.org/babble/20010708/msgs/69622.html