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Re: Wellbutrin. Sustained Release vs Imediate

Posted by Glenn Fagelson on June 5, 2001, at 21:12:44

In reply to Re: Wellbutrin. Sustained Release vs Imediate » Stephania, posted by terra miller on June 5, 2001, at 14:47:46

> > Hi all.
> >
> > What is the difference of the SR vs the imediate release? Are there different sides? How does a pdoc chose which is a good choice?

Hi, I threw-up(vomited)when taking the
IR form of Wellbutrin, going on Wellbutrin
SR took care of that. And I did not
experience the nervousness that I felt
with the Wellbutrin IR.
Glenn
>
>
> Hi,
>
> Theoretically, I think the SR version is probably better because it is supposed to make it so that the drug is more spread out. I think the side effects with the SR version are supposed to not be as hard as with the IR version.
>
> With the IR version, however, you are able to take less if that is where your body is at. The IR version comes in 75mg and 100mg tabs, whereas the SR version doesn't come in the 75mg tabs.
>
> With the IR, you have to take it 3-4 times a day (depends on dosage, etc.) instead of twice a day with SR.
>
> In my case, I seem to have a metabolism that just chews this stuff up. I started on SR and after 5 hours knew my body needed more. I was having really noticable peaks and lows on it. (I think my body must be backwards, because SR is supposed to help make it so that the peaks and lows aren't there!) So I switched to the IR version and take pills 4 times a day. It's more inconvenient for certain, but I don't have the peaks and lows like I did on the SR version. I also was able to start at a lower dose and work up more slowly since I'm taking 75mg tabs. In my body, the wellbutrin hits me hard and then slowly tapers off. So, taking the 75mg tabs means that I'm not hit so hard at first and taking it 4 times a day means remaining fairly level. That is just MY story however, and it seems to me to be so other than the norm that you probably just want to think of my case as one of those < 1% cases. I haven't heard of any others having to be so creative with their wellbutrin. *s*
>
> terra
>
> p.s. there's a great link to an RX site (Sal????... Sal knows where it is) and it tells you about both the IR and the SR version. The side effects are about the same, but slightly different. I found it helpful, since most people take SR and I'm on IR. Sal put this link up under "links of the day" or something like that, within this month.


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poster:Glenn Fagelson thread:65413
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