Posted by SLS on June 2, 2001, at 11:07:56
In reply to Re: Lamictal -- PLEASE PLEASE advise » Briana, posted by SalArmy4me on May 31, 2001, at 17:18:13
Dear Sal,
> The fears over Lamictal (lamotrigine) rashes are unfounded.
I think using the word "unfounded" is deceptive and perhaps dangerous. I have known several people who have had the rash evolve early using a titration schedule more rapid than that suggested by the drug manufacturer. They were forced to discontinue Lamictal and restart it. Using the more gradual titration schedule, they were successful in establishing a therapeutic dosage. I don't know if this is related to the rash phenomenon, but I would experience an itch in the inner corner of both eyes upon dosage increases. This includes a dosage increase from 200mg to 300mg. This itch would last from a few hours to a day or so. It just so happens that this itch is similar to what I experience as a result of an allergy to oak tree pollen.
> The chance of having a mild to moderate rash are 3%--according to clinical trials.
In my opinion, 3% is large enough a number to warrant adherence to the prescribed titration schedule. Line up 33 people. 1 of them might die. Unacceptable.
Better to be safe...
- Scott
poster:SLS
thread:64875
URL: http://www.dr-bob.org/babble/20010530/msgs/65156.html