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Re: Neurontin replacing other medication/side effects » nike

Posted by SalArmy4me on June 1, 2001, at 11:42:06

In reply to Neurontin replacing other medication/side effects, posted by nike on May 30, 2001, at 13:46:43

Your gabapentin is being used all over to treat chronic pain, restless legs syndrome, bipolar disorder, and anxiety disorders (1). It may even be enough to cover for the Zoloft. The side-effects are minimal, and you will develop a tolerance quickly.
Gabapentin has no known abuse potential, has few side effects, does not require blood monitoring, and does not affect liver metabolism or the excretion of other medications (2). The mechanism of action for gabapentin is unknown. It may influence the synthesis of GABA and glutamate. These systems are known to modulate anxiety, arousal, and sleep. Gabapentin may also increase deep sleep(stages 3 and 4) by increasing serotonin levels.

Pollack MH, Matthews J, Scott EL: Gabapentin as a potential treatment for anxiety disorders. Am J Psychiatry 1998; 155:992-993
Beydoun A, Uthman BM, Sackellares JC: Gabapentin: pharmacokinetics, efficacy, and safety. Clin Neuropharmacol 1995; 18:469-481


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