Posted by paulk on May 30, 2001, at 20:30:49
In reply to Re: Codeine for Depression Treatment, posted by Elizabeth on May 30, 2001, at 17:19:52
> > Ive heard of this also about time-released addreal There is a need but no one does it
>Adderal? That's a once-daily stimulant...why would there be a need for a slow-release formulation?
No, its not usually used 2 3 times a day a mixture of different half-life amphetamines the idea is to have a tapering effect (which makes no sense if it is used in multiple dosages???). Adderal used to be marketed under a different name for weight loss use. I tried it to overcome the memory problems I started having with Effexor with out good results. I got one day of good effect followed by a week of diminished returns tried upping the dose then a week of really nasty withdrawals.It is also used for ADD but Ritalin is generally preferred because of its longer half-life.
> > If that 1 is yourself it is always interesting. How long has it been working for you sounded like a some of the patients were only getting a few weeks worth of relief.
>That's a concern I've had, but it seems to be the exception rather than the rule. I've been taking it for about 6 months. (I had tried it before, a few years ago, but quit after a couple months because of side effects.)
> > >Demerol is atypical in that it's relatively excitatory compared with morphine.
> > Put me right to sleep.
>Demerol has a toxic metabolite (normeperidine) that's very proconvulsant. ("Excitatory" just means that it increases neuronal firing, BTW.)
It is a very big danger to anyone taking an MAOI. Single does have been fatal.> > >Cocaine is a nonselective monoamine reuptake inhibitor (dopamine, norepinephrine, and serotonin). Medically, cocaine is used only as a local anaesthetic -- very different from systemic use as a psychostimulant.
>
> > I wonder if a slow release formula might be a good drug?>Nomifensine -- an antidepressant that was withdrawn from the market about 15 years ago -- is a NE-DA reuptake inhibitor. It was supposed to be very effective, in particular for people who'd had no success with other ADs.
> > >Yes, some people have said they've successfully augmented ADs with naltrexone. That surprises me, since it's supposed to be a not-very-pleasant drug.
>
> > Didnt bother me at all per haps a bit of a headache the first day.>It's variable, obviously. I would expect it to be neutral at best, tho'. It came as a huge surprise to hear that some people got an AD effect from it. (To my knowledge, it only works in combination with an AD, but even that was something I never would have guessed.)
I can only guess at the reasoning for it being a possible AD induced sex dysfunction remedy perhaps some people get an endorphin response that could interfere with sex makes some sense orgasm produces lots of endorphin.
poster:paulk
thread:64320
URL: http://www.dr-bob.org/babble/20010530/msgs/64800.html