Posted by SalArmy4me on May 16, 2001, at 0:32:21
In reply to feelin bad again, posted by mstar on May 15, 2001, at 12:20:21
Effexor has dose-dependent effects on the uptake pumps for serotonin and then norepinephrine. At 75-150 mg/day, venlafaxine is predominantly a serotonin reuptake inhibitor (SRI) like the SSRIs. At 300 mg/day, it produces comparable norepinephrine uptake inhibition to an NSRI such as desipramine...Your depressed brain may be lacking that norepinephrine boost gained only by a higher dose of Effexor {thus, this may be why the Effexor does not work for you right now}.
poster:SalArmy4me
thread:13781
URL: http://www.dr-bob.org/babble/20010515/msgs/63187.html