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Re: Seratonin Syndrome » mytwogrlsmom

Posted by SalArmy4me on May 11, 2001, at 23:17:28

In reply to Seratonin Syndrome, posted by mytwogrlsmom on May 11, 2001, at 22:59:21

What the actual occurrence of serotonin syndrome is in the fluoxetine/phentermine combination I don't know, but there have been cases of it. Ask your doctor about that combo. These cases may or may not be clinically relevant to your treatment regimen:

Goldberg, Richard J. MD. Selective Serotonin Reuptake Inhibitors: Infrequent Medical Adverse Effects. Archives of Family Medicine. 7(1):78-84, January 1998.
"...It {serotonin syndrome} has been reported from the combination of fluoxetine and phentermine, an amphetamine-like appetite suppressant with sympathomimetic properties. This reaction occurred 8 days after discontinuation of fluoxetine when one 30-mg tablet of phentermine was added to the patient's treatment regimen. The patient developed severe physical and psychological activation with stomach cramps, palpitations, and tremors.

Bostwick, John Michael MD. Brown, Thomas M. MD. A Toxic Reaction From Combining Fluoxetine and Phentermine. Journal of Clinical Psychopharmacology. 16(2):189-190, April 1996.


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