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Re: Which ADs affect dopamine and norepinephrine?

Posted by sl on May 11, 2001, at 20:26:22

In reply to Re: Which ADs affect dopamine and norepinephrine?, posted by jamie on January 29, 2000, at 11:43:26

> Wellbutrin (Bupropion)

Which was going to be MY answer to the original question.
:)
Reprint from The SmithKlineBeecham website....

Pharmacodynamics: Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine, and does not inhibit monoamine oxidase. While the mechanism of action of bupropion, as with other antidepressants, is unknown, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.

sl


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URL: http://www.dr-bob.org/babble/20010507/msgs/62542.html