Posted by stjames on April 24, 2001, at 16:32:58
In reply to Re: Ecstasy use is safe, posted by mikes on April 24, 2001, at 12:35:00
> Also, taking an SSRI up to six hours after the ecstasy may prevent a good deal, if not all, of the neurotoxicity.
Not a good idea. Only animal studies show this. Even Dr. Shilgin thinks this is a bad idea. Shilgin also says animal neurology is more apt
to suffer damage from MDMA, making animals a poor choice to draw conclusions on effects to humans.Anyone talking about damage has not read the studies, as there are NO studies looking at long term effects. To be fair, it is hard to find perfict study subjects that just did MDMA, and nothing else, several years ago. Lots of studies show changes. No studies exist to see if changes are long term. We also do not know if these changes are good/bad or effect function. I can report for myself that after 200 + doses of MDMA, ~15 yrs ago, I have no change in function.
The whole parkinsons/movement disorder/dopamine connection to MDMA is bunk. MDMA does not effect dopamine. The press confused MDMA with the synthetic opioid MPTP (1-methyl-4-phenyl-
1,2,3,6-tetrahydropyridine). MPTP can appear as a contaminant from bad manufacture of a synthetic opiate, and has caused tragic neural damage to
unfortunate recipients of the contaminated black market opiate. MPTP bears no chemical relation to MDMA, and has not been associated with MDMA manufacture. MPTP kills most of the dopamine sights (receptors or producers, can't remember which)However, I have no question that MDMA can cause short term depression is many people. COME ON PEOPLE ! It is a very strong drug and Zen tells up for every high there is a low. This short term depression was evident in many of my friends and myself.
James
poster:stjames
thread:60822
URL: http://www.dr-bob.org/babble/20010424/msgs/61044.html