Posted by SLS on April 19, 2001, at 22:37:38
In reply to Lamotrigine Gabapentin., posted by JahL on April 19, 2001, at 20:19:41
Hi Jah.
I think there is sufficient reason for you to explore the combination of lamotrigine and gabapentin if you are bipolar. About a year ago, the NIMH published the life-chart of a patient with bipolar disorder whose depression was refractory to many antidepressant regimens. When they administered each of lamotrigine and gabapentin separately, lamotrigine proved partially effective while gabapentin was all but inert. When they combined the two, the patient remitted within a few weeks and was rated as being improved to a point of being symptom-free. Unfortunately, they didn't list the dosages used. Since then, they have continued working with the combination, but I don't know what are their impressions at this point. I wouldn't discourage you from trying the combination if you are unipolar, but I only know of its use in bipolar disorder.
You might consider increasing the lamotrigine to 200mg - 300mg before determining its usefullness.
- Scott
poster:SLS
thread:60514
URL: http://www.dr-bob.org/babble/20010417/msgs/60524.html