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Re: thoughts on active placebos and true efficacy?

Posted by mikes on April 16, 2001, at 23:23:16

In reply to Re: thoughts on active placebos and true efficacy? , posted by SLS on April 16, 2001, at 19:06:20

I don't think that ad's are a farce (how could they be, remember how the first maoi was discovered?), I was saying they working for maybe 20 percent. Which could still be true considering all of quitkin's writings. Furthermore, I am taking those writings with a grain of salt for two reasons. First, I don't have access to the actual paper (unless I want to spend seven dollars), and second, I haven't read any article that argues against Quitkin's findings. Quitkin is not God. I'm not going to believe what he says just because he is a doctor and can use big words.

> Frederick Quitkin, MD has addressed some of the issues involving the use and interpretation of placebos when studying the effectiveness of treatment modalities.
>
>
> - Scott
>
> ---------------------------------------------------------
>
> Validity of clinical trials of antidepressants.
>
> Quitkin FM, Rabkin JG, Gerald J, Davis JM, Klein DF.
>
> Department of Therapeutics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10698806&dopt=Abstract
>
> -------------------------------------------------------------
>
> Am J Psychiatry 1999 Jun;156(6):829-36
>
> Placebos, drug effects, and study design: a clinician's guide.
>
> Quitkin FM.
>
> New York State Psychiatric Institute, NY 10032, USA.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10360119&dopt=Abstract
>
> -------------------------------------------------------------
>
> Neuropsychopharmacology 1996 Oct;15(4):390-4
>
> Can the effects of antidepressants be observed in the first two weeks of treatment?
>
> Quitkin FM, McGrath PJ, Stewart JW, Taylor BP, Klein DF.
>
> Department of Therapeutics, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institution, New York 10032, USA.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8887993&dopt=Abstract
>
> --------------------------------------------------------------------
>
> Br J Psychiatry 1998 Sep;173:242-8
>
> Placebo run-in period in studies of depressive disorders. Clinical, heuristic and research implications.
>
> Quitkin FM, McGrath PJ, Stewart JW, Ocepek-Welikson K, Taylor BP, Nunes E, Delivannides D, Agosti V, Donovan SJ, Ross D, Petkova E, Klein DF.
>
> Department of Therapeutics, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institution, USA.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9926101&dopt=Abstract
>
> --------------------------------------------------------------


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URL: http://www.dr-bob.org/babble/20010411/msgs/60143.html