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Re: Wellbutrin: Dr. Richelson responds

Posted by Dr. Bob on April 14, 2001, at 23:30:58

In reply to Richelson: Wellbutrin, posted by Neal on April 11, 2001, at 18:42:55

> I noticed that on your slides that Wellbutrin was almost at the bottom of the list in terms of efficacy. Do you think that Wellbutrin is an efficacious anti-depressant?

Thanks for this question, which gives me the opportunity to clarify a point about the data that I presented. None of the transporter blocking potencies or the receptor blocking potencies is related to efficacy. It is assumed that all antidepressants are equally efficacious. The data presented give a first approximation to predict the likelihood of a drug causing certain adverse effects and certain pharmacodynamic drug interactions.


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