Posted by mikala_thompson on April 7, 2001, at 15:27:35
In reply to Scared About Wellbutrin's Long Term Effects, posted by JackD on August 26, 2000, at 3:48:59
from mentalhealth.com
Pharmacodynamics and Pharmacological Actions:
The neurochemical mechanism of the antidepressant effect of bupropion is not known. Bupropion does not inhibit monoamine oxidase. Compared to classical tricyclic antidepressants, it is a weak blocker of the neuronal uptake of serotonin and norepinephrine; it also inhibits the neuronal re-uptake of dopamine to some extent.Limited clinical data suggest a higher incidence of adverse experiences in patients receiving concurrent administration of bupropion and L-dopa. Administration of bupropion to patients receiving L-dopa concurrently should be undertaken with caution, using small initial doses and small gradual dose increases.
poster:mikala_thompson
thread:43766
URL: http://www.dr-bob.org/babble/20010403/msgs/59038.html