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Re: Any info on 5HT4 receptors? » SLS

Posted by Noa on March 13, 2001, at 17:35:09

In reply to Re: Any info on 5HT4 receptors?, posted by SLS on March 13, 2001, at 16:53:12

I found this, too.

http://www.tocris.com/serotonin.htm

I guess my next step is to better understand the timing of how nefazodone produces mcPP. Acc. to this articleon 5HT receptors, mcPP disrupts sleep, for example, but 5HT2 antagonists (nefazodone is one) enhance sleep (my experience with it), but I wonder if timing is a factor, if the mcPP is a metabolite of the nefazodone--does this mean it is essentially a breakdown product?

WOuld timing of dosing have an effect on the ratio of nefazodone:mcPP in my system at any one time and could changing the dosing time so that there isn't as much of a fluctuation in this ratio help to reduce the (suspected) effects of the mcPP on the bladder?


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