Posted by SalArmy4me on March 13, 2001, at 16:03:37
I have been on Selegiline for only two days at a dose of 60 mg in three divided doses. (I do not have Parkinsons' disease, but rather Treatment-Resistant Depression. I have taken every other antidepressant known to mankind). So far, I have noticed a moderate antidepressant effect after one hour of ingesting it, which I could never get from a placebo. And that is why I'm writing this, to alert others.
Selegiline should be known as the "alternative" MAOI, in that it has less of the side-effects of phenelzine or tranylcypromine. The main side-effect that I have with it is a powerful stimulating effect similar to one caused by buproprion. I have been taking 10 mg oxazepam along with selegiline in order to counter the anxiety produced by selegiline.
Notes:
--I don't think that selegiline has an antidepressant effect under doses of 40 mg per day.
--I don't know if selegiline has any sexual side-effects yet.
--100 of the Generic 5 mg capsules (you need 240 capsules for a months antidepressant supply) costs US $240 at Sav-On Drug Stores. That is expensive. However, medical insurance covers it.
--You have to drop almost every other antidepressant in order to take the MAOI selegiline, although there is only one reported case in history of Serotonin Syndrome (that is fact).
--You have to follow the MAOI diet (I won't, though. I didn't on phenelzine or tranylcypromine and didn't have a hypertensive crisis).
poster:SalArmy4me
thread:56408
URL: http://www.dr-bob.org/babble/20010310/msgs/56408.html