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Re: Amisulpride dosage

Posted by AndrewB on March 11, 2001, at 22:03:54

In reply to Re: Amisulpride dosage » AndrewB, posted by vince on March 10, 2001, at 4:48:09

Vince,


It think a trial with Mirapex, then a trial ziprasidone is a good idea. If both seem to help you can try both in combo.

Pharmacologically, Mirapex and low dose amisupride (or ziprasidone) don't counteract each other at the D2/D3 receptor. Both, when successfull, increase activity at the postsynaptic D2/D3 receptors. My personal experience was that Mirapex and amisulpride don't counteract one another. Another person's experience was that risperdal and Miarapex was an effective combo. Risperdal is more similar in its receptor action to ziprasidone than amisulpride.

There is the possibility that nonresponse to amisulpride may be a good indicator of response to Mirapex but we need more feedback from people like you to confirm if this is true or not.

I am also trialing something for prevention of poop out from amphetamines like dexedrine. If it works in the 30 day or so trial, I will pass the information onto others.


AndrewB


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