Posted by jb on March 9, 2001, at 15:50:08
Hi. I have extreme social phobia - presenting in front of groups, speaking in front of groups, being in one-on-one meetings with senior bosses, etc. I've tried a number of drugs: Nardil, Parnate, Klonopin, Valium, Remeron, Neurontin (Gabapentin), etc. Nardil and Klonopin seem to be the best combination, by far. But, Nardil makes me gain weight and makes for complete sexual dysfunction. Klonopin causes short-term amnesia, and is kind of a dumb drug, at least for me.
(Parnate was more activating, and with limited sexual dysfunction, but gave me a very dry mouth and noticeably slurred or slowed my speech pattern. It also was not nearly as effective as Nardil. I noticed little benefit from Gabapentin, Celexa, Remeron, or Valium.)
My question:
Has anyone tried a combination which works better for them?
(1) What about Selegiline (L-Deprenyl) at high doses, where it loses its selectivity for MAO-B, and inhibits MAO-A and MAO-B?
(2) What about Modafinil, or Modafinil to combat the amnestic effects of Klonopin?
(3) Any benefit from amisulpride, pagoclone or any other meds?
(4) I understand most of the SSRI's affect 5H-T2, and, therefore, sexual function. Those that affect 5H-T1 can cause some anxyiolitic benefit. Those that affect 5HT-3 tend to induce or prevent nausea, depending on their mode of action.
Thanks, a lot for any suggestions.
JB
poster:jb
thread:56025
URL: http://www.dr-bob.org/babble/20010302/msgs/56025.html