Posted by mannetje on March 6, 2001, at 22:06:36
In reply to Re: Reaction to Seroquel - A question for CAm » mannetje, posted by Cam W. on March 6, 2001, at 14:51:36
> Mannetje - I was just thinking out lod with the blood test idea. I was thinking just a genreal blood test to see if the fever was due to an infection or something like that.
>
> As for the pupilary dilation; if it has stopped, I would maybe chalk it up to cholinergic rebound thing with the withdrawl of Seroquel. This would be an idiosyncratic effect, as Seroquel really doesn't directly affect cholinergic receptors, but may in a round about way through alpha-adrenergic receptors or some other receptor. This is only a guess though. I truly don't know what is going on, but if it isn't a sustained reaction, I'd hazard a guess as it being a mild withdrawl effect, most likely without long term consequences. What does the doc say about the pupilary dilation?
>
> - Cam
Thanks again CAm. My son will see the pdoc
Thurs. He had a similar [ second] reaction today, far less severe but with fever, pupilary dilation and dizziness. This is after one day without seroquel.To have been a withdrawl effect th e first time it seems that it would have to be an effect on the risperdol from the seroquel emptying given that the first reaction occured about two hours before what was to be his next dose of seroquel.[ the titering had been 25 1st day, 50 second day, 75 mg third day. It was on the evening of the fourth day just before he was to take 100mg that he had the reaciton] He was then fine the following day and made it to a half day in school, took a test, altho depressed until after a walk. Fine until again in the evening had fever, pupilary dilation,dizziness. He reports that it is less severe than the night before. Just seems scary to try the seroquel again without much closer supervision. Thanks again
poster:mannetje
thread:55663
URL: http://www.dr-bob.org/babble/20010302/msgs/55783.html