Posted by JohnX on February 20, 2001, at 2:01:01
In reply to Re: Wellbutrin SR/etc/weight gain? » JohnX, posted by terra miller on February 19, 2001, at 20:52:42
Terra,I *think* my 1st submission of this was lost,
so excuse me if I entered this twice.Yeah, I found that Wellbutrin releaved anxiety.
Some people find it agitating.
I also found that Effexor caused the most anxiety
of all the meds and Effexor is indicated to treat
GAD (Generalized Anxiety Disorder).
So I laugh too ;). My 1st psychiatrist thought
I might have PTSD. I think I'm backwards also.PTSD is a somewhat complex treatment. Research
into the biological underpinnings has not garnered
as much attention as other disorders in the past.
But there is a lot of momentum gaining in this
area.Many psychotropic meds have shown to be effective
at treating PTSD, but generally no one medication
has shown much greater efficacy than another.
The SSRI's are generally the 1st line treatment
since they are most likely to help with anxiety.
Its not atypical for PTSD patients to get a
different response profile to meds than most others. The biology of PTSD patients tends to
show paradoxical differences to those with other
disorders. For example, most typical patients
with depression show abnormally high levels of
the hormone cortisol (released during stress),
whereas PTSD depressed patients will show
abnormally low levels. A lot of this has to do
with how the traumatic episode(s) leading to
PTSD have caused interference in the body's
normal response to stress.There are medications in the pipeline called
CRF-antagonists that normalize the stress response
system that will likely be an excellent 1st line
treatment for both PTSD and many other disorders.And yes, I did lose weight on Wellbutrin too. ;)
-John
> John,
>
> *laughing* My brain is SO backwards. (Picture pdoc rolling eyes in bewilderment!) We're trying to treat anxiety from PTSD. The SSRI's are totally unhelpful (send me into MAJOR depression), serzone was great (until I started swelling up from it?!), and I could never get rid of the shakes from Effexor even after gutting it out 5 weeks. So, I'm really hoping this med works.
>
> Does Wellbutrin cause weight gain? (I'm hoping it's just the GirlScout cookies.) But I don't think so. (grrrrr.)
>
> Terra.
> > Terra,
> >
> > I hope it goes well for you. Wellbutrin is a good
> > alternative to SSRI's. It has some advantages
> > like fewer sexual side effects. Also, it tends
> > to work well for people who are anergic (lack of
> > energy) & have lack of motivation or interest.
> >
> > You also may try Effexor if Wellbutrin doesn't
> > pan out. Effexor works on serotonin like the
> > SSRI's but at higher doses it also works on norepinephrine. Generally norepinephrine and
> > dopamine are more associated with anergia, lack
> > of motivation, etc. The SSRI's can help in these
> > areas too but they generally are more targeted to
> > symptoms of anxiety,panic,ocd. Both groups of
> > meds have the same response rate for depression.
> > But some people definately tend to do better with
> > the SSRI alternatives.
> >
> > Good Luck,
> > John
poster:JohnX
thread:54286
URL: http://www.dr-bob.org/babble/20010212/msgs/54439.html