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Re: Ondansetron for depression

Posted by PhoenixGirl on February 9, 2001, at 10:08:08

In reply to Re: Ondansetron for depression » PhoenixGirl, posted by Sulpicia on February 8, 2001, at 20:40:56

I don't know about modafinil. In my pill book, it says that people taking modafinil may get high. Also I read a study in which modafinil was found to be an effecting AD augmenting agent.
I know less about odansetron. I know that it is a serotonin antagonist, like a lot of antipsychotics, and antipsychotics can sometimes augment ADs.

> It has a section in it about new possible antidepressants. Odansetron, adrafinil, modafinil, catopril, and some others were in there.
>
> I'm not familiar with ondansetron but do remember seeing it mentioned in Dr. Bob's Psychopharmacology Tips -- search perhaps?
> The key here may be "possible" new ADs; my daughter was in a study that used modafinil as an add-on for the treatment of depression. The consensus of the grumblings [loud] of the study participants was that it did squat.
> True, this is merely anectdotal. The manufacturer is really pushing this drug for lots of uses. It recently failed in trials for attention deficit disorder, much to the stockholders' dismay.
> Perhaps the fact that ondansetron is grouped with modafinil should lead us to suspect that it's not going to be very useful?
> Not a scientific conclusion but perhaps a consumer's surmise.
>
> I hope you find something that helps you.
> S.


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poster:PhoenixGirl thread:53505
URL: http://www.dr-bob.org/babble/20010131/msgs/53591.html