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Re: Reboxetine/Ritilin for Depression?

Posted by Katz on January 24, 2001, at 10:26:47

In reply to Re: Reboxetine/Ritilin for Depression?, posted by SLS on January 24, 2001, at 7:31:41

> Hi Katz.
>
> I think the suggestions of SalArmy4me are good ones. Have you ever tried the tricyclic antidepressants like desipramine or nortriptyline? Both of these drugs are very noradrenergic, as is reboxetine, but exert effects in other areas. The side effects of these drugs are the mildest among the tricyclics. I find desipramine a bit energizing and serves to lessen the anxiety often associated with depression. Like most other drugs, startup side effects might occur, but it has been my experience that they lessen with time. If desipramine produces some of that "wired" feeling in the beginning of treatment, it will probably disappear by the end of the first week.
>
> Once you trial some of the other drugs and drug combinations suggested here, you may want to visit the tricyclics. It seems that desipramine is a more consistently effective antidepressant than is reboxetine.

Hi Scott,

Thank you for your kind suggestions. I have tried many tricyclics over the years. Infact, desipramine was that last one that I tried. Encouraged by its energizing effects intially, I soon became discouraged when all positive effects diminished after a four month trial. It is my belief that I have too much seratonin in my brain which is overwehlming and sedating my nor-adrenalin system and that is why the trycyclics are not working for me. I don't know if that makes any sense or not. I have never heard anyone else put forth this theory (although surely someone else must have). Whatever the reason, anything which increases seratonin is just too sedative for me. As for nortriptyline, that sounds very familiar is that one of the older tricyclics, elivil or tofrinil? If so I have been on it and found it to be the most sedating of all...sleeping around the clock!

Wishing you happiness,

Katz
>
>
> - Scott
>
>
>
> > After reading so many positive things about Reboxetine, I ordered some from IAS and eagerly began a course of 8mg/day to treat my depression, anhedonia and social phobia. On or about day four, I began to feel the energizing effects which were encouraging. One particular day into week two, I actually felt almost "happy". I was filled with child like awe as I watched the snow falling outside my window. WOW! Is this what normal feels like I thought! This is cool! My next thought was, "this is to good to be true. I can't last." IT DIDN'T!!! Here I am at the end of week three and the energizing effects that I felt in the beginning seem to have waned. I never did experience any of the other positive results I was hoping for. No increase in socialability, no motivation, no increased self-esteem...none of that good stuff! As I begin week four, I have increased my dosage to 10mg/day. I have little hope that this is going to be the miracle pill I have been waiting for most of my adult life.
> >
> > I was wondering if anyone suffering from depression, anhedonia and social phobia has had any positive results with this drug? How long did it take for you to get full relief from your symptoms?
> >
> > Several years ago I was seeing a pdoc several states away who prescribed ritilin. At 20 mg/day, it was my miracle pill! I found complete relief from depression, anhedonia and social phobia. I remained on ritilin for 6 months. I took 20mg in the morning only. I never needed to increase the dose. Unfortunately, I could not afford the expense of traveling 3 states away every month (gas, motel, food, etc). I tried unsuccessfully to find someone in my area to prescribe the ritilin for me. All refused and insisted on more trials of anti-depressants! I have tried them all. They don't work! Three years have since past. 3 more years of my life wasted because nobody was willing to prescribe a drug that is handed out indiscriminantly to children as though it were candy! Who's crazy here?
> >
> > Has anyone used ritilin or another stimulant to successfully treat depression, anhedonia and social phobia? Any input would be greatly appreciated. I'm desperate. I want a life! HELP!!!
> >
> > Katz


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