Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: serzone-Myasthenia Gravis ?? » SLS

Posted by mars on January 7, 2001, at 15:06:27

In reply to Re: serzone-Myasthenia Gravis ?? » mars, posted by SLS on January 3, 2001, at 9:17:56

Hiya Scott ~

Thank you for your lucid response. I'll forward it on (w/o your name) to my pdoc. I don't think the info about serotonin syndrome was around in '97 when I first had the problem - do you know?

As far as doctors being wrong, well, I'm afraid I'm used to that ;-) I was misdiagnosed at 14 and had such horrible experiences with the helping professions that I avoided them for the next ten years. When I finally did start doing meds again in '89 I was quite active in learning about what was out there (my dad's a PhD in pharmacology and would give me textbooks to read). Unfortunately, I let that go the past years, in part because I finally ended up in the care of a pdoc who was able to diagnose me as Bipolar II (she's an Akiskal follower) and came to rely on her perhaps a bit too much. That's why I'm here now, trying to be more, um, proactive again.

I'd been doing the parnate/lithium thing since '95, which had barely kept me able to work, and we'd negotiated dosages starting low and working up. But by the time the leg problem occurred it was clear that parnate wasn't cutting it for me anyway ~ the divorce, increase in job stress, and the myasthenia episode didn't help either, ha ha. In between then and now I've tried a number of drugs. Effexor isn't great but I haven't really been functional the past year and a half anyway, and at least I'm not thinking about suicide all the time. A major piece of the puzzle has been added lately ~ I've been diagnosed with fetal alcohol effects. Not sure how to handle that yet, been a bit overwhelming.

I'd love to get the advice of you and the other great folks on babble, but my medical history is so long I'm not sure how to start. I guess this is it. :)

Thanks again,

mary

> Hiya Mars.
>
> It may have been a manifestation of a serotonin syndrome. Lithium has been known to induce serotonin syndrome when it is combined with a drug that has pro-serotoninergic properties. These would include:
>
> Prozac - fluoxetine
> Zoloft - sertraline
> Luvox - fluvoxamine
> Paxil - paroxetine
> Celexa - citalopram
> Serzone - nefazodone
> Desyrel - trazodone
> Anafranil - clomipramine
> Nardil - phenelzine
> Parnate - tranylcypromine
>
> In addition, using any two of the drugs listed here has the potential to produce serotonin syndrome.
>
> The leg thing is very reminiscent of something I experienced when I was taking a very powerful MAOI and using trazodone for sleep. I think it is likely that Parnate + lithium may have produced in you a mild serotonin syndrome that caused asthenia and/or changes in muscle tension making it difficult to walk.
>
> Your doctors may have been wrong. While the Parnate + lithium combination may have been the culprit, it is generally a great combination when treating difficult cases. Perhaps you only needed 300mg-600mg.
>
>
> - Scott



Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:mars thread:50304
URL: http://www.dr-bob.org/babble/20001231/msgs/51093.html