Posted by cole on January 4, 2001, at 11:35:47
In reply to Re: Remeron Poop-out?, posted by SLS on January 4, 2001, at 7:17:06
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> Hey Cole.
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> The appetite thing you experienced is supposed to be a trait of Remeron. At lower dosages, hunger is increased via H1 histamine receptor blockade. At higher dosages, it is thought that the effects of Remeron to block norepinephrine alpha-2 receptors becomes predominant and lowers appetite. This pattern also occurs with sedation, I believe.
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> A friendly suggestion: Once you find again a therapy that works, STICK with it. Your depression returned for one of two scenarios. Either you relapsed for not taking Remeron for long enough before discontinuing it, despite your not having a recurrent-type depression, or you have a recurrent-type depression and require continuous treatment indefinitely. It is far too common a story that someone arbitrarily discontinues an effective treatment, only to relapse and remain less responsive to the same medication.
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> At the very least, in my opinion, you should take an effective antidepressant for 12 - 14 months. If you relapse within the first 4 months after discontinuation, you might as well consider yourself a "lifer".
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> Good luck.
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> - ScottI recognize the role my discontinuation may have played in this current depression, but it doesn't do much to realize that now. I stopped the remeron for a month to try reboxetine, and found that the rebox didn't do it for me. At 60mg this summer my appetite was completely out of control, although I did only take it for 3 months and perhaps it would have lessened over time then too. I do realize that remeron could be my life saver, but it has stopped working and that is really frightening, since I am either non-responsive or get agitated with the other psych meds. Is there anything that you know of that I can do now, or have I basically painted myself into a corner? Thanks for taking the time to respond.
poster:cole
thread:50869
URL: http://www.dr-bob.org/babble/20001231/msgs/50890.html