Posted by J. Lester on December 9, 2000, at 17:40:03
In reply to SAM-e?mifon questions again : liver enzymes, posted by Maniz on December 9, 2000, at 15:03:21
Hello :
> Modafinil (Provigil) is supposed to be like Adrafinil but without the liver problems. Although, JohnL posted here (search for
> his posts)that Adrafinil works better than Modafinil.
> The mayor side effect of Modafinil seems to be on your pockets. < joke >> I think if you are under a doctor care you can have the liver tests and be advised to discontinue Adrafinil if necessary. I do not
> know if it can cause a permanent damage. I think eleveted liver enzimes does not necessarily means tissue damage, but I am no
> doctor.Well, I am self-medicated with Olmifon. If I only knew which enzymes are affected ... Most serious
info on Olmifon is probably in French.> Sure you have tried other drugs that have an effect on NA like wellbutrin right? (was the class name RIMAOAs?).
Yes, wellbutrin does not work for me, TCAs are best.
> Regarding treatment resistant depression, I have read some success stories using SAM-e. Have you tried it?. Of course it is a
> much milder substance, but effcetive too and has some "good" side effects. SAM-e is used to treat liver problems. Must be
> taken on an empty stomach and in whole pill because it is enteric coated.> Sam-e is a mthylating agent and it is suggested to use together with folate and B6 (and maybe TMG to incerease effect) so not
> to elevate homocistein. Again, mayor problem is price. Sad, because from experience I think it works.
> At www.consumerlabs.com there is a list of good brands.Yes, SAMe is expensive, not tried yet. Supplements I took were St.Johns Wort, DMAE, 5HTP, phenylalanine, tyrosine.
I stick with L-tyrosine - a 'megadose' of 8 - 10 gram in morning. It is supposed to increase
NA + dopamine, and to a lesser degree serotonin (?). It works fine for me as to bringing my mental pain
to the level of zero emotions, no positives, no negatives, just indifference, melancholy,
but not higher ..., sadness remains whatever dose I take. Seems like only serotonin is affected.J.L.
poster:J. Lester
thread:50273
URL: http://www.dr-bob.org/babble/20001130/msgs/50285.html