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Re: Poll regarding Prozac response and nonresponse

Posted by JohnL on November 9, 2000, at 3:39:03

In reply to Poll regarding Prozac response and nonresponse, posted by anita on November 8, 2000, at 19:42:59

> Hi,
>
> I'd like to find out if people who had no response or a negative response to Prozac had a good response to any of the following meds:
>
> Zoloft
> Lamotrigine
> Neurontin
> Risperidone
> Zyprexa
>
> Conversely, I'd like to know if people who had a good response to Prozac had no response to the above meds.
>
> Thanks very much for your input.
>
> anita

Anita,
I've had about a 50% good response to all the above including Prozac. The exception is Neurontin which is the only one I have not tried.

In most clinical studies, not all, a 50% or more reduction of depression scores is commonly the benchmark utilized to determine whether a drug is successful or not. If that is the case, then all the above were helpful to me. The problem is that if someone has a 50% improvement, well, they're still depressed. Not as depressed, but still depressed. It also doesn't account for individual symptom clusters, such as anhedonia in my case, in which all the above drugs were failures.

So yes I had a good response to all the drugs listed, but not a complete response to any of them.
John


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poster:JohnL thread:48467
URL: http://www.dr-bob.org/babble/20001102/msgs/48506.html