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Bipolar Disorder - 30% more neuronal synapses ?

Posted by SLS on November 2, 2000, at 23:52:02

Bipolar Disorder: 30% higher density of synapses in specific brain structures.

Study size: 16 patients


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Medline Abstract:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11007716&dopt=Abstract

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Dr. Koop: Full article

http://www.drkoop.com/news/stories/october/hs/mood_swings.html


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Introduction:

Too Many Brain Cells Mean Mood Disorder
Mood Swings Linked to Overstimulation

Oct. 3, 2000

Julia McNamee Neenan
HealthSCOUT

If you've got a severe mood swing disorder, your brain is not only physically overpacked with cells, but they may be firing so much that the brain can't filter out all the stimulation, says a new study.

In those with bipolar disorder, two major areas of the brain contain 30 percent more cells that send signals to other brain cells, says a report in today's American Journal of Psychiatry. The extra signal-sending cells may lead to a kind of overstimulation, which makes sense considering the symptoms of bipolar disorder, says the study's lead author, Dr. Jon-Kar Zubieta. He is an assistant professor of psychiatry and nuclear medicine at the University of Michigan at Ann Arbor.

 

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