Posted by anita on October 29, 2000, at 18:48:09
In reply to Types of Weight Gain on Meds, Probably Revisited, posted by shellie on October 27, 2000, at 22:06:55
Hi Shellie,
Some hypothesize that H1 antagonism or 5HT2C antagonism can be involved in weight gain. However, these neurotransmitters aren't antagonized by Lamictal or nardil, as far as I know. They're mainly implicated in antipsychotic weight gain.
While I didn't seem to add any weight when I added Lamictal to nardil, I did lose a lot of weight very quickly when I went off nardil. Since I had edema on nardil, I too thought that maybe water retention had something to do with the weight gain. I used spironolactone, a diuretic, on and off for PMS, but it didn't affect my weight.
Some people lose weight on Topamax (200mg or more), a new mood stabilizer, and take it (experimentally) for weight gain with other meds.
anita
> Since my relapse into severe depression, the best combination for me has been nardil and lamictal. But as I was increasing the lamictal, my weight was going up. Also I had a lot of discomfort in my breasts. I did not experience an increase in appetite, so my eating didn't increase, and I was doing the treadmill.
>
> I tried dieretics but it didn't seem to help. Yet within less than two weeks after stopping the lamictal I lost 9 pounds (not dieting or exercising).
>
> My question is can you lose nine pounds in such a short time without it being water retention? The dieretic I took always works for me premenstrually, so I know it has been effective.
>
> The reason I am asking this question, is that I am so tired of being depressed and wouldn't hesitate to go back on the lamictal if I didn't gain weight. But I was scared that I would get to be a huge person and I have enough problems with self-image not to deal with that.
>
> Any ideas about the mechanisms of weight gain and such a fast loss? Shellie
poster:anita
thread:47577
URL: http://www.dr-bob.org/babble/20001022/msgs/47709.html