Posted by R.Anne on October 29, 2000, at 15:58:34
In reply to Meridia and Prozac, fatal combo?, posted by angelrose on October 25, 2000, at 23:06:17
Hi Angelrose,
I just visited drkoop's site and looked up meridia and prozac-I was curious, too! Here is what it said:There are 2 interactions for Meridia and Prozac :
1 severe, 1 medium, and 0 mild (1 is a drug/drug interaction , 1 is a food/drug interaction).
1. Severe Interaction between Prozac (generic: fluoxetine) and Meridia (generic: sibutramine)The risk for serotonin syndrome may be increased if these two drugs are coadministered. Serotonin syndrome is a rare, but serious adverse effect which requires immediate medical attention and may exhibit reactions such as excitement, hypomania, restlessness, loss of consciousness, confusion, disorientation, anxiety, agitation, myoclonus, dysarthria, tachycardia and emesis. The mechanism is probably due to additive serotonergic effects. The concomitant use of these drugs is not recommended.
References:
1. Anonymous. Product Information. Meridia (sibutramine). Knoll Pharmaceutical Company, Whippany, NJ. PROD; : .
--------------------------------------------------------------------------------
2. Medium Food Interaction for Meridia (generic: sibutramine)
The risk for serotonin syndrome may be increased if tryptophan is coadministered with sibutramine. Serotonin syndrome is a rare, but serious adverse effect which requires immediate medical attention and may exhibit reactions such as excitement, hypomania, restlessness, loss of consciousness, confusion, disorientation, anxiety, agitation, myoclonus, dysarthria, tachycardia and emesis. The mechanism is probably due to additive serotonergic effects. The concomitant use of these drugs is not recommended.
References:
1. Anonymous. Product Information. Meridia (sibutramine). Knoll Pharmaceutical Company, Whippany, NJ. PROD; : .
In case you didn't look it up I thought you might want to know how dangerous it can be. Best wishes to you! r.anne*******
> Hi,
> Has anybody tried Meridia for weight loss?
> I know Meridia and Prozac taken together could possibly cause serotonin syndrome.
> Just wondering if anybody has tried them simultaneously.
> I'm desperate to lose weight and I cannot seem to do it, no matter how much or how little I eat.
> The only way I have been able to lose weight is taking a vacation from my meds. but at this point I cannot imagine doing this.
>
> Suggestions, comments, advice, as always much appreciated.
> Thanks!
poster:R.Anne
thread:47378
URL: http://www.dr-bob.org/babble/20001022/msgs/47703.html