Posted by JohnL on October 25, 2000, at 3:01:48
In reply to Can Celexa cause depression?, posted by JC Godin on October 24, 2000, at 11:28:06
JC,
Any psychiatric medication can cause worsening of symptoms, including Celexa. This is for several reasons. In some people, certain medications don't bind properly at a molecular level. Just a poor fit. The pieces of the puzzle just don't go together. A possibility exists that you don't have low serotonin, but instead low norepinephrine. If that's the case, increasing serotonin will only further decrease the norepinephrine. And the possibility exists that your malfunctioning chemistry isn't related to neurotransmitters at all, but instead to chemical or electrical instability, in which case any antidepressant would be the wrong choice.There are two schools of thought that I personally endorse. One is conventional psychiatry. The other is the Jensen method. Both of these though have the same thing in common at this point in your treatment. That is, other serotonin antidepressants should be tried and compared. You may likely find one to be a whole lot better than Celexa for you.
I too can get worse on higher doses. It happened with Zoloft, Paxil, Prozac, and Serzone. As doses were increased, I got worse than I ever was to begin with. Nearly suicidal. Medication related, no doubt whatsoever. Ultimately in time I discovered the best for me was a subtherapeutic dose of Prozac (5mg to 10mg a day), with the addition of another medication that enhances other things instead of serotonin. Not sure where your treatment will lead, but the highest priority at this time should be to try another antidepressant. In a perfect world, you could try three...maybe Effexor, Zoloft, Prozac, for example...for just two weeks each, and then choose your favorite of the three for a longer trial. You'll almost certainly discover you really like one a lot more than the others if given the chance. Sadly it's not a perfect world. Regardless, trying any other antidepressant besides Celexa is probably warranted at this time.
John
poster:JohnL
thread:47249
URL: http://www.dr-bob.org/babble/20001022/msgs/47312.html