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Re: just started zyprexa

Posted by Rapunzel on October 13, 2000, at 23:29:13

In reply to Re: just started zyprexa , posted by TK on October 11, 2000, at 22:36:35

> My MD started me on Zyprexa x5 days ago. I am also on Ativan daily as needed and also Wellbutrin 2x a day. I just came off Effexor and Seroquel following a suicidal incident. I am being treated for depression. I feel agitated and irritable then cry for no reason. Has anyone had this side effect w/Zyprexa? Has anyone had positive experiences w/this new drug?

TK - Yes, your irritability and agitation could be from the zyprexa. I did not have any problems while I was on zyprexa, but one of my fellow study patients did. She described her symptoms as being like extremely severe PMS, but she did not find these side-effects too debilitating and did not drop out of the study. All the study patients were on 7.5mg.
As my original post stated, I was involved in a drug study of zyprexa's effects on trichotillomania, an illness not related to depression, psychosis, or schizophrenia - and my reactions may differ significantly from those who do have those illnesses. My problems with depression did not surface until I stopped zyprexa. While on the medication, the only significant side-effects I experienced were extreme drowsiness in the morning and weight gain, although I did have extreme agitation(mental and physical) if i missed a dose. I am now convinced that my depressive episode was related to the extremely short half-life of the drug and a too short weaning period. According to the dr. running the study, I am the ONLY person out of the millions to have taken this med to experience this complication. And my response is: and how many of those millions were taking it to combat trichotillomania?
I can't help wondering why your dr. prescribed zyprexa for depression. My study dr. says that it has a very slight function as an SSRI, but I have never heard of it being prescribed strictly for depression. Do you have other secondary problems that he/she might be trying to combat?
Good luck combating your depression. It is truly the worst thing I have ever experienced. Sorry this was so long, but I try to be thorough!


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