Posted by AndrewB on October 4, 2000, at 9:03:08
In reply to Is Gabapentin a Stimulant?, posted by Orin3 on October 3, 2000, at 21:49:14
Your response to gabapentin is atypical but not rare.
See Dr. Bob's Tips Section under 'side-effects of gabapnetin' for stories similar to yours.
Dr. Goldstein, who specializes in treating patients with Chronic Fatigue Syndrome, has reported that many of his patients experience increased energy with this med. He also notes it can be a very effective anxiolytic and can improve mood in some.
I believe this paradoxical effect you've experienced indicates a correction of some kind of underlying neurotransmitter system dysfunction. Which neurotransmitter system is the question. Obviously Gabapentin increases GABA release but explanation of its stimulatory effect lie elsewhere. Goldstein mentions it increases activity at Ketamine receptors. But I don't know what activity gabapentin may also have on other nuerotramitter systems. Maybe a call to Dr. Goldstein's office (http://www.drjgoldstein.com/frames/05artbook.html) will be able to clarify things.
Consider yourself lucky to have stumbled onto this.
AndrewB
poster:AndrewB
thread:45767
URL: http://www.dr-bob.org/babble/20000926/msgs/45776.html