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Re: Half-life of Effexor

Posted by Mark H. on October 3, 2000, at 20:47:26

In reply to Re: Half-life of Effexor, posted by stjames on October 3, 2000, at 1:36:48

I would just chime in with my usual litany that for those of us who are kept awake or suffer from achy, jumpy legs half the night when we take Effexor after about 2 or 3 p.m., it is MUCH better to take a single, largish dose after breakfast (to buffer your stomach) and to avoid the extended release version altogether. This accomplishes a couple of things: it lets the Effexor wear off quite a bit before trying to sleep, and for some of us who experience "mornings are horrible and I get better as the day wears on," the timing is right to help with depression. One caution: I have to be careful WHAT I eat for breakfast, or the food can bind the medication and I don't experience a full effect. Drinking lots of water seems important as well.

I'm glad to hear the XR version works well for others. You might plan on building up to 75 - 150mg a day before you get anything like continuous relief (in my experience).

Best wishes,

Mark H.


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