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Re: Serzone / My brief experience

Posted by noa on September 24, 2000, at 14:21:03

In reply to Re: Serzone / My brief experience, posted by MarkinBoston on September 21, 2000, at 17:07:36

Mark, I am on the serzone/effexor combo, too, and it works pretty well for me. These two sort of balance each other out . I take 300 mg serzone at 6 pm-ish, and 300 effexor xr in the morning. I also take ritalin, which I think helps but is not an Essential component of my cocktail, and I take synthroid and cytomel, both of which are very definitely major players in controlling my depression, as I have hypothyroid.

The serzone counters the insomnia and restlessness and agitation of the effexor. Together they provide sufficient antidepressent effect. The serzone is somewhat sedating, but not overwhelmingly so. If I take it at 6, I can fall asleep at 10. I first tried taking it before bedtime, but that didn't work. I couldn't fall asleep for a long time, and then was still groggy in the morning.

One issue with serzone for me (and I've read others' similar accounts here) is that there are INITIAL effects that are very bothersome, like emotional lability, rage, grogginess, and balance/coordination problems. BUT, all of these went away after 3-4 weeks.

Good luck, I hope the combo continues to work for you.


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